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A Safety Study of the Administration of Mesenchymal Stem Cell Extracellular Vesicles in the Treatment of Recessive Dystrophic Epidermolysis Bullosa Wounds Opening Soon


This trial is a prospective, open label, randomized, multi-center study, with intra-subject paired- wound control, intended to assess the safety and preliminary efficacy of administering EVs derived from allogeneic MSCs

Study Details
Internal Title: AGLE-102-101

PCH IRB Number: IRB-23-345
Clinical Trials Government Identifier: NCT04173650

Diagnoses & Treatments: Mesenchymal stem cells, Recessive Dystrophic Epidermolysis Bullosa, EB

Study Type: Clinical Trial

Eligibility: 6 years or older, diagnosis of Dystrophic EB with wounds with size between 10-50cm squared on arms, legs, or trunk

Enrollment Status: Opening Soon

Phase: I/II


Contact Email:


Principal Investigator

Principal Investigator Photo
Division Chief, Pediatric Dermatology