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Feasibility Trial of Optune for Children with Recurrent or Progressive Supratentorial High-Grade Glioma or Ependymoma, and Feasibility and Efficacy Trial of Optune in Conjunction with Radiation Therapy for children with Newly Diagnosed DIPG - Amendment 1 Open


This is a multicenter trial of the Optune device to examine the feasibility and to describe the device-related toxicity in children in Stratum 1 and efficacy of concurrent Optune and standard focal radiation therapy in Stratum 2.

Study Details
Internal Title: PBTC-048

PCH IRB Number: IRB-23-411
Clinical Trials Government Identifier: NCT03033992

Diagnoses & Treatments: High-grad glioma, DIPG, recurrent/refractory ependymoma, Optune, TTFields, cancer

Study Type: Investigational Device

Eligibility: Diagnosis for respective stratum, Stratum 1: Patient must be = 5 but = 21 years of age, Stratum 2: Patient must be = 3 but = 21 years of age

Enrollment Status: Open

Phase: I/II


Coordinator Contact: BRIANNA LENT
Contact Email: