Involves 3 steps to improve detection and treatment of fetal complete AVB. 1) screen high titer anti-Ro, 2) FHRM to identify 2° AVB, 3) IVIG and Dex for moms who detect abnormality with the hope of reversing 2° AVB before it becomes permanent (3°).
Study Details
Internal Title:
STOPBLOQ
PCH IRB Number:
S-IRB-20-322
Clinical Trials Government Identifier:
NCT04474223
Diagnoses & Treatments:
Heart Block, Fetal Atrioventricular Block, AVB, Arrhythmias, Cardiovascular diseases, Dexamethasone, Anti-Ro, Fetal Heart Rate Monitor, FHRM,
Study Type:
Clinical Trial
Eligibility:
<18 weeks pregnant at the time of enrollment, =18 years of age; excludes multi-fetal pregnancies, Known allergic reactions to components of IVIG, or dexamethasone or maternal IgA deficiency
Enrollment Status:
Open
Phase:
III