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A Multi-Institution Study of TGFß; imprinted, Ex Vivo Expanded Universal Donor NK Cell Infusions as Adoptive Immunotherapy in Combination with Gemcitabine and Docetaxel in Patients with Relapsed or Refractory Pediatric Bone and Soft Tissue Sarcomas Open


A study to evaluate the safety and efficacy of Universal Donor NK Cells in combination with Gemcitabine and Docetaxel in patients with relapsed/refractory pediatric bone and soft tissue sarcoma.

Study Details
Internal Title: Cell Therapy TiNKS Trial MCC21704

PCH IRB Number: IRB-REL-25-185
Clinical Trials Government Identifier: NCT05634369

Diagnoses & Treatments: sarcoma, cancer, bone cancer, soft tissue cancer, relapsed sarcoma, refractory sarcoma, NK cell, cellular therapy

Study Type: Clinical Trial

Eligibility: 2 to 40 years of age, diagnosis of relapsed/refractory sarcoma, at least one and no more than four total lines of cytotoxic systemic treatments

Enrollment Status: Open

Phase: I/II


Coordinator Contact: BRIANNA LENT
Contact Email:


Principal Investigator