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LOGGIC/FIREFLY-2: A Phase 3, Randomized, International Multicenter Trial of DAY101 Monotherapy Versus Standard of Care Chemotherapy in Patients with Pediatric Low-Grade Glioma Harboring an Activating RAF Alteration Requiring First-Line Systemic Therapy Open


A study evaluating tovorafenib (DAY101) monotherapy versus standard of care chemotherapy in patients with Low-Grade Glioma (LGG).

Study Details
Internal Title: Day101-002

PCH IRB Number: IRB-23-073
Clinical Trials Government Identifier: NCT05566795

Diagnoses & Treatments: LGG, Low-Grade Glioma, Tovorafenib, DAY101, Cancer

Study Type: Clinical Trial

Eligibility: 0-17 Years Old, Low-Grade Glioma Diagnosis

Enrollment Status: Open

Phase: III


Coordinator Contact: ROXANNE SANDOVAL
Contact Email:


Principal Investigator