IMPACCT: Infrastructure for Musculoskeletal Pediatric Acute Care Clinical Trials
Pediatric medial epicondyle fractures (MEF) and displaced distal radius fractures (DRF) are common injuries. This multicenter study will help improve clinical outcomes by comparing reduction and casting with patient surveys.
|
Platform to Assess Influenza and COVID-19 Vaccine Effectiveness in Underserved Arizona Populations
The project's objective is to know how many people are getting sick with flu or COVID-19 and what kinds of antibodies they are producing to these viruses.
|
A Phase II Randomized Controlled Trial of Soluble Fiber Supplementation for Asthma
The overall goal of this study is to determine whether fiber supplementation in children with Asthma leads to better asthma outcomes. If you participate in the study you will take a questionnaire and potentially ingest soluble fiber with a normal diet. Blood, nasal wash and stool will be collected pre- and post-fiber consumption. This a study presented by Southwest Health Equity Research Collaborative (SHERC), in collaboration with NAU and Phoenix Children's Hospital.
|
Pediatric Influence of a Cooling duration on Efficacy in Cardiac Arrest Patients (P-ICECAP)
To determine whether increasing durations of cooling are associated with better outcomes
|
TITRE: TRIAL OF INDICATION BASED TRANSFUSION OF RED BLOOD CELLS IN ECMO
This study will determine if indication-based RBC transfusion based on reduced tissue oxygen delivery, compared with RBC transfusion based on institutional-specific threshold reduces organ dysfunction in critically ill infants and children on ECMO.
|
Surveillance and Treatment to Prevent Fetal Atrioventricular Block Likely to Occur Quickly (STOPBLOQ)
Involves 3 steps to improve detection and treatment of fetal complete AVB. 1) screen high titer anti-Ro, 2) FHRM to identify 2° AVB, 3) IVIG and Dex for moms who detect abnormality with the hope of reversing 2° AVB before it becomes permanent (3°).
|
Intrathecal 2-Hydroxypropyl-ß-cyclodextrin for Neurological Decline in Patients with Niemann-Pick Disease Type C1
This is a study for intrathecal treatment of NPC
|
A Randomized Trial to Evaluate Sequential vs Simultaneous Spectacles plus Patching for Amblyopia in Children 3 to <13 Years Old
A randomized trial to determine whether simultaneous treatment with spectacles and patching has an equivalent VA outcome compared with sequential treatment in children 3 to <13 years of age
|
Predictors and Determinants of Pediatric Immunity
The goal of this project is to identify and enroll patients with potential inborn errors of immunity (IEI) and then use next generation DNA sequencing and analysis to identify causative candidate gene variants.
|
LOGGIC/FIREFLY-2: A Phase 3, Randomized, International Multicenter Trial of DAY101 Monotherapy Versus Standard of Care Chemotherapy in Patients with Pediatric Low-Grade Glioma Harboring an Activating RAF Alteration Requiring First-Line Systemic Therapy
A study evaluating tovorafenib (DAY101) monotherapy versus standard of care chemotherapy in patients with Low-Grade Glioma (LGG).
|