IMPACCT: Infrastructure for Musculoskeletal Pediatric Acute Care Clinical Trials
Pediatric medial epicondyle fractures (MEF) and displaced distal radius fractures (DRF) are common injuries. This multicenter study will help improve clinical outcomes by comparing reduction and casting with patient surveys.
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Understanding and Targeting the Pathophysiology of Youth onset Type 2 Diabetes
Provide innovative critical information regarding the unique natural history of glycemic control, insulin sensitivity, and ß-cell function, and their mechanistic determinates, in obese adolescents at risk for developing type 2 diabetes.
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Platform to Assess Influenza and COVID-19 Vaccine Effectiveness in Underserved Arizona Populations
The project's objective is to know how many people are getting sick with flu or COVID-19 and what kinds of antibodies they are producing to these viruses.
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Pediatric Influence of a Cooling duration on Efficacy in Cardiac Arrest Patients (P-ICECAP)
To determine whether increasing durations of cooling are associated with better outcomes
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BBD Longitudinal Study of Osteogenesis Imperfecta
The overall goal of this study is to answer specific questions about the natural history of brittle bone diseases as defined by molecular etiology and to develop the foundation for prospective clinical studies.
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A Phase II Randomized Controlled Trial of Soluble Fiber Supplementation for Asthma
The overall goal of this study is to determine whether fiber supplementation in children with Asthma leads to better asthma outcomes. If you participate in the study you will take a questionnaire and potentially ingest soluble fiber with a normal diet. Blood, nasal wash and stool will be collected pre- and post-fiber consumption. This a study presented by Southwest Health Equity Research Collaborative (SHERC), in collaboration with NAU and Phoenix Children's Hospital.
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Intrathecal 2-Hydroxypropyl-ß-cyclodextrin for Neurological Decline in Patients with Niemann-Pick Disease Type C1
This is a study for intrathecal treatment of NPC
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TITRE: TRIAL OF INDICATION BASED TRANSFUSION OF RED BLOOD CELLS IN ECMO
This study will determine if indication-based RBC transfusion based on reduced tissue oxygen delivery, compared with RBC transfusion based on institutional-specific threshold reduces organ dysfunction in critically ill infants and children on ECMO.
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A Randomized Trial to Evaluate Sequential vs Simultaneous Spectacles plus Patching for Amblyopia in Children 3 to <13 Years Old
A randomized trial to determine whether simultaneous treatment with spectacles and patching has an equivalent VA outcome compared with sequential treatment in children 3 to <13 years of age
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Feasibility Trial of Optune for Children with Recurrent or Progressive Supratentorial High-Grade Glioma or Ependymoma, and Feasibility and Efficacy Trial of Optune in Conjunction with Radiation Therapy for children with Newly Diagnosed DIPG - Amendment 1
This is a multicenter trial of the Optune device to examine the feasibility and to describe the device-related toxicity in children in Stratum 1 and efficacy of concurrent Optune and standard focal radiation therapy in Stratum 2.
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